News

What causes interference in short-term memory?

principal investigator of the research of project 201/20 - The Control of Attentional Diversion: A Psychophysiological Approach, supported by the BIAL Foundation, carried out three experiments that explored the effects of changing-state vibrotactile sequences on short-term memory. The results revealed that short-term memory for a visual sequence is more disrupted by a changing-state vibrotactile sequence (alternating from one hand to the other) compared to a steady-state tactile sequence (presented to both hands simultaneously).

Nominations for BIAL Award in Biomedicine 2023 are open until June 30

The third edition of the BIAL Foundation's international award, the BIAL Award in Biomedicine, is open, with nominations until June 30. With the amount of 300.000 Euros, this award seeks to recognise a work published in the broad biomedical field within the last ten years, the results of which are considered of exceptional quality and scientific relevance.

The role of alpha in attentional processes

Alexander Jones and Jonathan Silas published in Cortex the paper Spatial attention is not affected by alpha or beta transcranial alternating current stimulation: A registered report resulting from the research project 150/16 - An investigation into the causal role of alpha oscillations in attention, supported by the BIAL Foundation. Using transcranial alternating current stimulation (tACS), the researchers tested whether somatosensory alpha oscillations are causally related to endogenous and exogenous attention and concluded that the manipulation of alpha by tACS does not cause changes in tactile spatial attention. These findings support an account of alpha power not being causally involved in attention.

Italy, UK, USA and Portugal were the countries with most supported projects in Grants Programme 2022/23

Did you know that in the Grants Programme for Scientific Research 2022/23 it was supported 75 applications from 17 countries?

Voluntarily turning off consciousness

Matthew Sacchet, principal investigator of project 99/20 - Beyond "mindfulness" and toward a modern science of meditative mastery and spiritual transformation, supported by the BIAL Foundation, studied the total absence of consciousness during meditation achieved by some advanced practitioners. Besides the absence of any time experience or tiredness, practitioners also report a sudden sense of clarity, openness, and possibly insights after emerging from meditation-induced cessations of consciousness.

Maria de Sousa Award: applications until May 31

The Portuguese Medical Association and the BIAL Foundation are promoting the third edition of the Maria de Sousa Award, launched in 2020 to honour the memory of the physician and great researcher Maria de Sousa. The Maria de Sousa Award aims to award and support young Portuguese researchers, aged 35 or under, with scientific projects in the area of Health Sciences, including a mandatory internship in an international center of excellence.

BIAL Foundation celebrates its 29th anniversary

Today, the BIAL Foundation celebrates 29 years of activity in three areas with the aim of stimulating new discoveries and contributing to the improvement of human life: the attribution of Awards, the Grants Programmes for Scientific Research and the “Behind and Beyond the Brain” Symposia.

Structural analysis of hippocampal astrocytes

João Filipe Oliveira, principal investigator of the research project 37/18 - Decoding the neuron-astrocyte dialogue that supports cognitive processing, supported by the BIAL Foundation, published the paper Astrocyte structural heterogeneity in the mouse hippocampus in the journal GLIA. The author concludes that “the main finding of this work is that hippocampal astrocytes display structural heterogeneity across hippocampal subfields that is conserved along the dorsoventral axis.”

The role of TrkC in the regulation of fear

In the scope of the research project 85/18 - Role of NT3/TrkC in the regulation of fear, supported by the BIAL Foundation, the principal investigator, Mónica Santos, published in the journal Molecular Neurobiology the paper TrkC Intracellular Signalling in the Brain Fear Network During the Formation of a Contextual Fear Memory. It was observed an overall decrease in TrkC activation in brain fear network (amygdala, hippocampus, and prefrontal cortex), both in the consolidation and reconsolidation phases of fear memory formation. In particular, the most relevant differences were observed in the amygdala during the consolidation phase and in the hippocampus during the reconsolidation phase of fear memory. In fact, consolidation and reconsolidation of contextual fear memories are dually dissociable processes that recruit different pathways.

Nuno Grande Doctoral Scholarship 2022 winner is already known

Daniel Guimarães de Oliveira is the winner of the Nuno Grande Doctoral Scholarship 2022, an initiative of the family of Professor Nuno Grande, the School of Medicine and Biomedical Sciences (ICBAS) and the BIAL Foundation.

The incidence of NDE in ICU survivors

The research team led by Charlotte Martial assessed the incidence of near-death experiences (NDEs) among patients who survived a prolonged stay (i.e. > 7 days) in intensive care units (ICU), regardless aetiologies. Out of the 126 included patients, 15% reported having experienced an NDE. Higher frequency of dissociative symptoms and a greater spiritual and personal well-being were the strongest predictors for the recall of NDE. One year later, the NDE was not significantly associated with quality of life. These results were reported in the paper Incidence of near-death experiences in patients surviving a prolonged critical illness and their long-term impact: a prospective observational study published in the journal Critical Care and arise from the research project Characterization of “Near-Death Experiences” through the comparison of experiencers and non-experiencers’ particularities: inter-individual differences in cognitive characteristics and susceptibility to false memories, supported by the BIAL Foundation.

Is supplementary motor area involved in automatic control of behavior?

Ignacio Obeso, principal investigator of the research project 230/18 - Unraveling the mechanisms behind automatic and emotional control: Psychophysiological, cortical excitability and functional connectivity measures, supported by the BIAL Foundation, aimed to test the possible direct role of supplementary motor area (SMA) in automatic and voluntary response inhibition by resourcing to two noninvasive brain stimulation (NIBS) inhibitory techniques over SMA, namely repetitive transcranial magnetic stimulation (rTMS) and transcranial static magnetic field stimulation (tSMS). Participants received both real and sham NBS techniques over SMA. No relevant impact of treatment (rTMS, tSMS) or condition (real, sham) was seen in the training or test phases of a go/no-go learning task and a stop signal task. It seems that SMA has a reduced or indirect involvement in automatic control of behavior. These results are detailed in the paper The supplementary motor area and automatic cognitive control: Lack of evidence from two neuromodulation techniques published in the Journal of Cognitive Neuroscience.

Can childhood trauma cause insomnia in adults?

Research has shown that adverse childhood experiences result in more dysfunctional ways of shame coping and increase the severity of insomnia in adulthood.

Near-death experiences among ICU survivors

Research with 126 patients admitted to ICU for at least 7 days reveals that 15% reported having experienced a near-death experience.

Elderly people can improve episodic memory by neurostimulation of the cerebellum

A study demonstrated that neurostimulation of the cerebellum led to improvements in episodic memory performance in healthy elderly individuals.

Does aging change the way we interpret face processing of emotion?

Study shows that aging may hamper the neural processing of facial expressions of emotion.

Hypnosis, meditation, and prayer: which is most helpful for pain management?

Researchers found that a single session of hypnosis and mindfulness meditation, but not prayer, may be useful for managing acute pain.

Does playing with parents at home make it easier for young children to adapt to preschool?

A study showed that children with higher levels of oxytocin adapt better to their preschool environment and that playing with their parents increases those levels.

Can gratitude buffer the negative effects of stress?

Researchers found that gratitude has a unique stress-buffering effect on both reactions to and recovery from acute psychological stress.

Do mood fluctuations impact confidence in decision-making?

Study reveals that in the healthy adult population, fluctuations of mood do not interfere with confidence in decision-making.

Relationship between sleep bruxism, insomnia and anxiety

Researchers concluded that, although sleep bruxism has no direct association with insomnia, anxiety may act as a bridging factor between these complaints.

Can IQ and socioeconomic status interfere with children's reading fluency?

Researchers found that Intelligence Quotient (IQ) plays no role with reading fluency deficits in children, unlike socioeconomic status.

Do rats recognize musical melodies like humans?

Study reveals that rats showed sensitivity to track harmonic and temporal patterns in music and such sensitivities might be shared across species.

Evening people show enhanced fear acquisition, which may increase the risk to develop anxiety

Researchers resorted to the classic Pavlovian paradigm of fear conditioning to study the association between chronotype and fear responses in healthy humans.

The quest of physiological markers for the experience of pain

Researcher: Elia Valentini - Department of Psychology & Centre for Brain Science, University of Essex Summary: The aim of this project is to improve measurement of the human experience of pain by investigating a combination of psychophysical and physiological responses during mild noxious stimulation. More specifically, we want to investigate how sensitive and specific to pain the brain oscillatory responses are. We use EEG as the main technique, but we are keen to collaborate with neuroscientists using fMRI, autonomic measures and brain stimulation as well as with computational neuroscientists. A clinical collaborator would also be very much welcome.

EEG investigation of hypnosis and decision-making

Researcher: Rinaldo Livio Perri - University Niccolò Cusano Rome, Italy Summary: I work in the field of hypnosis and cognitive neuroscience. In particular, I adopt the event-related potentials (ERPs) to investigate the effect of the hypnotic suggestions on sensory processing and cognitive performance. I am an expert in decision-making and proactive brain processes before the stimulus administration (e.g., the perceptual, prefrontal and premotor readiness during the expectancy stage). I could help colleagues to properly analyze the ERP signal in the pre-stimulus stage of processing. Also, I would be happy to share my EEG data for re-analyzing them in the frequency domain (e.g., wavelet or coherence analysis in the hypnosis research). Feel free to contact me for any question! More information on my papers: https://scholar.google.it/citations?user=-8e_V64AAAAJ&hl=it Possible collaborations: neuroscientist with experience in the EEG frequency analysis Email: perri.rinaldo@gmail.com

Transparent Psi Project - looking for collaborators

Summary: We are running a fully transparent, expert consensus-base multilab replication of Bem’s (2011) experiment 1. The project features state of the art methods to maximize transparency and study integrity. The study involves a computerized experiment taking about 20 minutes per session. Group testing is possible in a computer lab, no specialized equipment needed. Labs are expected to recruit at least 100 participants. Participants will be exposed to images with explicit erotic/sexual content in the experiment. No financial compensation is required for the participants. Data collection is expected to take place in the 2020 fall semester. Every material is provided for ethics/IRB submissions and data collection in English (translation of materials might be necessary by the collaborators). The study is pre-registered and the manuscript is accepted in principle for publication in the journal Royal Society Open Science. All collaborators who meet the minimum sample size criterion will get authorship on this paper reporting the results of the replication study. More information in the preprint: https://psyarxiv.com/uwk7y/ Indicate interest in the collaboration via the following form: https://tinyurl.com/tpp-labs With any question contact the lead investigator: Dr. Zoltan Kekecs, kekecs.zoltan@gmail.com

Cognitive control and learning

Researcher: Ignacio Obeso, Ph.D. / CINAC - HM Puerta del Sur Summary: The aim of our projects is to understand the behavioral and neural mechanisms used to learn how humans establish adaptive behaviour in changing contexts. More specifically, we want to decipher how stopping abilities are initially learned and later executed under automatic control. We use task-related fMRI, brain stimulation and clinical models to test our predictions in laboratory settings as well as online home-based paradigms. Possible collaborations: computational scientist Email contact: i.obesomartin@gmail.com https://iobesomartin.wixsite.com/cognitivecontrol